Perfectionism is acknowledged as a core vulnerability and a perpetuating factor in several psychopathologies. The purpose of the present study was to investigate the effectiveness of short-term psychodynamic/interpersonal group psychotherapy for perfectionism and perfectionism-related distress such as anxiety, depression, and interpersonal problems. This study is a quasi-experimental study applying clinical trial method and contains pre-test, post-test, follow-up periods and control group. The study population included students and the sample consisted of 30 people with extreme perfectionism, who were assigned in two groups of 15 people, experimental and waiting list groups using randomized block design. Research instruments included Tehran Multidimensional Perfectionism Scale, Perfectionistic Self Presentation Scale, Perfectionistic Cognition Inventory, Beck Depression Inventory-II, Beck Anxiety Inventory and Inventory of Interpersonal Problems-32. In order to analyse the collected data, mixed analysis of variance and Repeated Measures Analysis of Variance were used in SPSS software version 22. The results show that the intervention in the experimental group compared to the waiting list group caused a clinically and statistically significant decrease in the mean scores. This result is observable and evident in all levels of perfectionism and psychological distress (anxiety, depression and interpersonal problems), except for the subscale of Non-Display of Imperfection from the Perfectionistic Self Presentation Scale. These results were preserved through the follow-up periods. These results show that short-term dynamic/interpersonal group therapy is effective in treating most of the components of perfectionism and concerning its effectiveness; it reduced psychological distress and showed that the components pertaining to perfectionism are factors of vulnerability in this regard.